diff --git a/.github/actions/setup-backend/action.yml b/.github/actions/setup-backend/action.yml
index db3ff7a78..1910f4851 100644
--- a/.github/actions/setup-backend/action.yml
+++ b/.github/actions/setup-backend/action.yml
@@ -42,12 +42,12 @@ runs:
     - name: Install dependencies
       run: |
         if [ "${{ inputs.install-superset }}" = "true" ]; then
-          sudo apt-get update && sudo apt-get -y install libldap2-dev libsasl2-dev build-essential
-          pip install --upgrade pip setuptools wheel
+          sudo apt-get update && sudo apt-get -y install libldap2-dev libsasl2-dev
+          pip install --upgrade pip setuptools wheel uv
           if [ "${{ inputs.requirements-type }}" = "dev" ]; then
-            pip install -r requirements/development.txt
+            uv pip install --system -r requirements/development.txt
           elif [ "${{ inputs.requirements-type }}" = "base" ]; then
-            pip install -r requirements/base.txt
+            uv pip install --system -r requirements/base.txt
           fi
         fi
       shell: bash
diff --git a/Dockerfile b/Dockerfile
index 9a89cef35..60ba12eab 100644
--- a/Dockerfile
+++ b/Dockerfile
@@ -85,7 +85,7 @@ RUN if [ "$BUILD_TRANSLATIONS" = "true" ]; then \
 
 # Transition to Python base image
 FROM python:${PY_VER} AS python-base
-RUN pip install --no-cache-dir --upgrade setuptools pip
+RUN pip install --no-cache-dir --upgrade setuptools pip uv
 
 ######################################################################
 # Final lean image...
@@ -191,7 +191,7 @@ RUN --mount=type=bind,source=./docker,target=/docker \
 
 # Install Playwright and its dependencies
 RUN --mount=type=cache,target=/root/.cache/pip \
-    pip install playwright \
+    uv pip install --system playwright \
     && playwright install-deps
 
 # Optionally install Chromium
diff --git a/docker/pip-install.sh b/docker/pip-install.sh
index 2defc7d1e..7e69a6efb 100755
--- a/docker/pip-install.sh
+++ b/docker/pip-install.sh
@@ -47,10 +47,10 @@ fi
 # Choose whether to use pip cache
 if $USE_CACHE; then
   echo "Using pip cache..."
-  pip install "${ARGS[@]}"
+  uv pip install --system "${ARGS[@]}"
 else
   echo "Disabling pip cache..."
-  pip install --no-cache-dir "${ARGS[@]}"
+  uv pip install --system --no-cache-dir "${ARGS[@]}"
 fi
 
 # Remove build-essential if it was installed
diff --git a/superset/__init__.py b/superset/__init__.py
index cbab58e0d..c97580b12 100644
--- a/superset/__init__.py
+++ b/superset/__init__.py
@@ -34,7 +34,8 @@ from superset.security import SupersetSecurityManager  # noqa: F401
 # All of the fields located here should be considered legacy. The correct way
 # to declare "global" dependencies is to define it in extensions.py,
 # then initialize it in app.create_app(). These fields will be removed
-# in subsequent PRs as things are migrated towards the factory pattern
+# in subsequent PRs as things are migrated towards the factory
+# pattern
 app: Flask = current_app
 cache = cache_manager.cache
 conf = LocalProxy(lambda: current_app.config)